Book Review: Pharmacology of Gastrointestinal Motility and Secretion

The gastrointestinal pharmacology of cannabinoids: focus on motility.

The marijuana plant Cannabis sp. and its derivatives and analogues, known as cannabinoids (CBs), induce many effects throughout the whole body. Herein we briefly review the gastrointestinal (GI) pharmacology of CBs, with special focus on motor function. Some drugs are available to treat nausea and emesis, and evidences in humans and animal models suggest that other GI motility alterations (gast...

Book Review: Gastrointestinal Physiology and Diseases Methods and Protocols

Gastrointestinal Motility

Anatomic regions of the stomach are the fundus, corpus (body), antrum and pylorus. The functional regions of the stomach do not correspond to the anatomic regions. Functionally, the stomach can be divided into the gastric reservoir and the gastric pump (Fig. 1). The gastric reservoir consists of the fundus and corpus. The gastric pump is represented by the area at which peristaltic waves occur:...

Gastrointestinal Motility

Gastrointestinal (GI) motility is an essential function of digestive and absorptive processes of the gut, required for propelling intestinal contents, mixing them with digestive juices, and preparing unabsorbed particles for excretion. Pivotal to the discussion of mechanisms for producing defined patterns of motor responses are important and intimately related aspects of intestinal neurophysiol...

Relaxin and gastrointestinal motility.

Relaxin is involved in a variety of functions. Among them, relaxin influences gastrointestinal motility in mice mainly regulating the biosynthesis of nitric oxide, considered as the main substance causing smooth muscle relaxations. Relaxin is able to regulate the different nitric oxide synthase expression depending on the gut region considered. Relaxin also counteracts the hypermotility state, ...